We hereby present different DNA nanocarriers consisting of new multimodular systems (MMS), containing the cationic lipid dioleylaminesuccinylparomomycin (DNA MMS DOSP), or bis (guanidinium)-tren-cholesterol (DNA MMS BGTC), and DNA lipid nanocapsules (DNA LNCs).Active targeting of the asialoglycoprotein receptor (ASGP-R) using galactose as a ligand
Chloride intracellular input crank channel proteins (CLICs) are multi-functional proteins that are expressed in various cell types and differ in their subcellular location.Two CLIC homologs, EXL-1 (excretory canal abnormal like-1) and EXC-4 (excretory canal abnormal- 4), are encoded in the Caenorhabditis elegans genome, providing an excellent model
ABSTRACT Human parainfluenza virus 3 (HPIV3) infection is driven by the coordinated action of viral surface glycoproteins hemagglutinin-neuraminidase (HN) and fusion protein (F).Receptor-engaged HN activates F to insert into the target cell membrane and drive virion-cell membrane fusion.For F to mediate entry, its precursor (F0) must first be cleav